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Upfront Ventures

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Overview

Who we areUpfront Ventures is LA’s original venture firm, backing breakout companies at the earliest stages. With $2B+ AUM and over 25 years of investing, we lead early rounds in healthtech, biotech, and beyond—supporting founders from first check through scale.
Value addI started my career as a clinician because I wanted to help people heal — and I bring that same lens to investing. I’ve led clinical strategy at scaling startups, built partnerships across payers and providers, and lived the complexity of care delivery from the inside. I back founders building what should already exist — and roll up my sleeves to help them do it.
Firm typeVC
Global HQ

1314 7th St, Santa Monica, CA 90401

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Thesis

Funding requirementsWe invest in healthtech, biotech, life sciences, digital health, diagnostics, therapeutics, care delivery, value-based care, healthcare SaaS, mental health, women’s health, aging, AI/ML in healthcare, and regulated healthcare services.
Funding stages1. Idea or Patent2. Prototype3. Early Revenue4. Scaling
LeadAlways
Check size$1M to $8M
Target countriesFlag of UK UKFlag of USA USAFlag of Canada Canada

Team

Christina FattoreAssociate
Clinician turned operator turned investor - backing HC companies solving real problems by people who actually care.

Portfolio

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Linkedinhttps://www.linkedin.com/company/upfront-ventures/
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Websitehttps://upfront.com/
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