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Deeptech Investors & VC Firms

Browse OpenVC's database of investors funding startups in deeptech, AI, and advanced engineering.

Last update: August 15, 2025

List author: Lucas Roquilly

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The Ultimate Guide to Deep Tech VC and Venture Capital Firms for Startup Founders

The Deep Tech revolution is here, reshaping industries from healthcare and agriculture to energy. For founders, the prospect of building a Deep Tech startup is both exhilarating and daunting. While the potential to create game-changing products and transform industries is undeniable, securing funding for a Deep Tech venture is not your typical fundraising hustle.

Deep Tech investment is a unique niche that demands a robust plan, technical expertise, and patience. This guide will walk you through the world of Deep Tech VC, how to connect with the right investors, and how to prepare your startup for funding. Whether you’re working on the next breakthrough in AI, biotech, or robotics, this guide has you covered.

What is Deep Tech?

Deep Tech refers to startups that are grounded in high-impact scientific research and engineering innovation. Unlike traditional tech companies that often focus on software and user experience, Deep Tech ventures work on solving fundamental problems in areas like:

  • Artificial Intelligence \=: Pioneering applications in machine learning and computer vision.
  • Robotics: Creating smarter, autonomous systems for industries like manufacturing or agriculture.
  • Biotechnology: Advancing fields such as gene editing and synthetic biology.
  • Nanotechnology: Developing high-performance materials and components.
  • Clean Energy: Innovating sustainable energy solutions like hydrogen fuel cells and carbon capture.

Deep Tech vs. Traditional Tech Investments

Traditional tech investments often seek traction and market validation through user acquisition or revenue generation within short timelines. Deep Tech, on the other hand, requires long-term vision and patience. Here's why:

  • Longer R\&D cycles: Deep Tech startups thrive on groundbreaking innovation, which takes years to develop.
  • Higher capital requirements: Building a prototype in Deep Tech often requires substantial funding upfront.
  • Regulatory hurdles: Deep Tech solutions in areas like healthcare or energy often need to pass extensive regulatory approvals before hitting the market.

Why Scalability and Sustainability Rule

Deep Tech investments are high-risk, high-reward. Startups need to show not only the creative genius behind their solutions but also how they plan to scale and sustain their impact over time. Investors need to believe your innovation isn’t just academically impressive but commercially viable.

Top Venture Capital Firms Investing in Deep Tech

Looking for the big players in the Deep Tech VC space? Here are prominent firms making waves in the industry:

  1. Lux Capital
    • Focus Areas: AI, robotics, biotech, and space tech.
      • Notable Investments: Anduril, Zoox, Heliogen.
      • Insight: Lux Capital thrives on risky bets where technology intersects with big, world-changing ideas.
  2. Data Collective DCVC
    • Focus Areas: Artificial intelligence, machine learning, and computational science.
      • Notable Investments: Planet Labs, Recursion, Benchling.
      • Insight: DCVC specializes in funding data-driven enterprises tackling hard science innovation.
  3. SOSV
    • Focus Areas: Biotech, food tech, robotics, and hardware.
      • Notable Programs: IndieBio and HAX for early-stage support.
      • Insight: They provide not just funding but a strong mentorship ecosystem for hard tech founders.
  4. Sequoia Capital
    • Focus Areas: A versatile investment approach including early-stage Deep Tech startups.
      • Notable Investments: Graphcore, Skydio.
      • Insight: Although Sequoia is a household name, their increasing involvement in Deep Tech highlights the shift towards longer-term bets.
  5. Bold Capital Partners
    • Focus Areas: Future-forward technologies like biotech and quantum computing.
      • Notable Investments: Virgin Hyperloop, Moderna.
      • Insight: Bold Capital is closely aligned with startups tackling existential challenges.

Top Funded Deep Tech Startups

Want inspiration? These Deep Tech startups are setting the bar for innovation while securing major funding:

  • OpenAI: Leading advancements in artificial intelligence with applications ranging from natural language processing to autonomous systems.
  • Samsara: Revolutionizing IoT sensors for logistics and industrial analytics.
  • Cellares: Innovating personalized medicines and biologics manufacturing.
  • Commonwealth Fusion Systems: Developing breakthrough clean fusion energy solutions.
  • Deep Genomics: Using AI to accelerate precision medicine in biotechnology.

Key Factors Deep Tech Investors Look For

Deep Tech investors evaluate startups differently than traditional software companies. Here’s what you need to highlight when pitching to Deep Tech VC firms:

1. Regulatory Strategy

Especially in healthcare, energy, and biotech, outline a clear roadmap for navigating regulatory hurdles like FDA approval or CE certifications.

2. Market Fit

Deep Tech products must address clear problems. Show data that confirms a strong market demand and explain how your product is uniquely suited to solve it.

3. Capital Efficiency

Given the nature of Deep Tech, projects can quickly burn through cash. Demonstrate your ability to allocate resources wisely, particularly during the R\&D and prototyping stages.

4. Scalability and Sustainability

Highlight the long-term vision for scaling your product and ensuring sustainability. Convince investors your solution goes beyond one-time innovation to provide recurring value.

5. Business Model and Financial Projections

Don’t just focus on the technology; focus on the business. Show investors how your product will make money, the market size it taps into, and your plan for initial traction.

Emerging Industry for Deep Tech

Know these four hot trends if you want to get investor attention:

How to Prepare Your Deep Tech Startup for Investment

Here’s a practical roadmap to polish your pitch and prepare for investor meetings:

  • Develop a regulatory roadmap specific to your industry.
  • Show strong market validation through pilot programs or partnerships.
  • Keep financial projections realistic but compelling.
  • Build traction stories with quantifiable metrics, no matter how basic.
  • Ensure your pitch deck spotlights the problem you’re solving, the scale of opportunity, and your unique solution.

Using OpenVC to Find Deep Tech Investors

Finding the right investors can be overwhelming, which is why OpenVC exists to simplify your fundraising process.

Steps to Get Started:

  1. Filter Smartly: Use OpenVC to filter investors by stage, sector (Deep Tech), and check size.
  2. Discover Insights: Browse investor profiles to see who’s actively funding startups like yours.
  3. Submit Quickly: Upload your pitch deck directly and reach out to potential investors instantly.
  4. Monitor Progress: Use the built-in CRM to manage conversations, track engagements, and close your round.

Find the Best Deep Tech Investors and VC Firms on OpenVC

It’s time to make your fundraising process faster, easier, and smarter. Whether you’re tackling AI-driven healthcare or revolutionizing energy systems, OpenVC connects you with Deep Tech investors who share your vision.

Set your Deep Tech startup up for success. Create your free OpenVC account today and start finding investors who will back your venture.

Frequently Asked Questions

OpenVC is a free fundraising platform where startup founders can search verified investors,  submit their pitch decks, and manage their entire raise. Users can search 20,000+ verified investors, shortlist the right ones, and submit your pitch deck directly. Our CRM, deck analytics, and warm intro tools help you run a smarter, more organized raise.

Founders raise with OpenVC because it is designed to cut through the noise and get founders in front of the right investors, fast. With built-in tools for CRM, analytics, and warm intros, it helps you stay organized and improve your chances of getting a reply.

OpenVC is for early-stage startup founders who want to raise capital efficiently. Find investors from dozens of industries including SaaS, AI, fintech, biotech, and more. Whether you’re pre-seed, seed, or Series A, OpenVC helps you find and pitch aligned investors without paying intro fees, aimlessly cold-emailing, or scraping databases.

Yes, OpenVC is completely free to use. You can search investors, submit your pitch deck, track engagement, and manage your raise—all without paying a cent. Premium features are available, but the core platform is free and always will be.

You create a free OpenVC account, build your investor shortlist, and submit your pitch deck directly through the platform. Investors receive a unique link to view your deck, and you get analytics on who opens it and how long they spend on it. No cold emails, no guesswork. For more info, check out our complete guide to fundraising on OpenVC.

Absolutely, OpenVC is designed for early-stage fundraising. You’ll find thousands of angel investors, pre-seed VCs, accelerators, incubators, and family offices who are actively backing startups across sectors and geographies. Use OpenVC’s filters to narrow your search and find the right investors for your startup.

Some examples of startups that successfully secured funding through OpenVC include Mobly (2.5M seed), Paxum ($1.2M seed), and Laennec AI ($400k pre-seed). OpenVC startups have gone on to raise more than $1 billion from top venture capital firms like YC, Sequoia, Google Ventures, and M12.

OpenVC was created by Stephane Nasser and Lucas Roquilly—two founders building tools to make startup fundraising more transparent and accessible. We launched OpenVC to help founders find investors, get replies, and raise smarter. The platform is bootstrapped, community-driven, and built with a lot of heart.

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